diff --git a/package/python-boto3/python-boto3.hash b/package/python-boto3/python-boto3.hash
index a7e3ba6476..0a620aff21 100644
--- a/package/python-boto3/python-boto3.hash
+++ b/package/python-boto3/python-boto3.hash
@@ -1,5 +1,5 @@
 # md5, sha256 from https://pypi.org/pypi/boto3/json
-md5  8e39cbbb73c8eb861e2d2d7a5107c3d2  boto3-1.42.68.tar.gz
-sha256  3f349f967ab38c23425626d130962bcb363e75f042734fe856ea8c5a00eef03c  boto3-1.42.68.tar.gz
+md5  8f6916a7e50632593cdf56b5fcdbd365  boto3-1.43.1.tar.gz
+sha256  9e4f85a7884797ff0f52c257094730ed228aaa07fa8134775ff8f86909cf4f2a  boto3-1.43.1.tar.gz
 # Locally computed sha256 checksums
 sha256  0d542e0c8804e39aa7f37eb00da5a762149dc682d7829451287e11b938e94594  LICENSE
diff --git a/package/python-boto3/python-boto3.mk b/package/python-boto3/python-boto3.mk
index 7901c671a3..4a88e115cf 100644
--- a/package/python-boto3/python-boto3.mk
+++ b/package/python-boto3/python-boto3.mk
@@ -4,9 +4,9 @@
 #
 ################################################################################
 
-PYTHON_BOTO3_VERSION = 1.42.68
+PYTHON_BOTO3_VERSION = 1.43.1
 PYTHON_BOTO3_SOURCE = boto3-$(PYTHON_BOTO3_VERSION).tar.gz
-PYTHON_BOTO3_SITE = https://files.pythonhosted.org/packages/06/ae/60c642aa5413e560b671da825329f510b29a77274ed0f580bde77562294d
+PYTHON_BOTO3_SITE = https://files.pythonhosted.org/packages/98/36/028c12ed6ed85009a21b5472eb76c27f9b0341c6986f06f83475b40aaf51
 PYTHON_BOTO3_SETUP_TYPE = setuptools
 PYTHON_BOTO3_LICENSE = Apache-2.0
 PYTHON_BOTO3_LICENSE_FILES = LICENSE