diff --git a/package/pipewire/Config.in b/package/pipewire/Config.in
index 9d2de6c866..38a321d500 100644
--- a/package/pipewire/Config.in
+++ b/package/pipewire/Config.in
@@ -7,6 +7,7 @@ config BR2_PACKAGE_PIPEWIRE
 	select BR2_PACKAGE_ALSA_LIB_UCM if BR2_PACKAGE_ALSA_LIB
 	select BR2_PACKAGE_ALSA_LIB_SEQ if BR2_PACKAGE_ALSA_LIB
 	select BR2_PACKAGE_BLUEZ5_UTILS_PLUGINS_AUDIO if BR2_PACKAGE_BLUEZ5_UTILS # runtime
+	select BR2_PACKAGE_FFMPEG_SWSCALE if BR2_PACKAGE_FFMPEG
 	help
 	  PipeWire is a server and user space API to deal with
 	  multimedia pipelines.
diff --git a/package/pipewire/pipewire.hash b/package/pipewire/pipewire.hash
index 2e6a9ae3aa..8e701bfd4b 100644
--- a/package/pipewire/pipewire.hash
+++ b/package/pipewire/pipewire.hash
@@ -1,4 +1,4 @@
 # Locally calculated
-sha256  7670f617220cc053948fc8f2c1ff788192479ef5d4f373d878ac8a7cab76a71c  pipewire-1.2.8.tar.bz2
+sha256  2fdf073869bd171d29a92dc6857979864b53e3dc1a79ac76c15db78e5b12d9f8  pipewire-1.6.6.tar.bz2
 sha256  8909c319a7e27dbb33a15b9035f89ab3b7b2f6a12f8bcddc755206a8db1ada44  COPYING
 sha256  be4be5d77424833edf31f53fc1f1cecb6996b9e2d747d9e6fb8f878362ebc92b  LICENSE
diff --git a/package/pipewire/pipewire.mk b/package/pipewire/pipewire.mk
index c1dc2aa0cc..c5127b9a9d 100644
--- a/package/pipewire/pipewire.mk
+++ b/package/pipewire/pipewire.mk
@@ -4,7 +4,7 @@
 #
 ################################################################################
 
-PIPEWIRE_VERSION = 1.2.8
+PIPEWIRE_VERSION = 1.6.6
 PIPEWIRE_SOURCE = pipewire-$(PIPEWIRE_VERSION).tar.bz2
 PIPEWIRE_SITE = https://gitlab.freedesktop.org/pipewire/pipewire/-/archive/$(PIPEWIRE_VERSION)
 PIPEWIRE_LICENSE = MIT, LGPL-2.1+ (libspa-alsa), GPL-2.0 (libjackserver)
@@ -70,13 +70,13 @@ endif
 
 ifeq ($(BR2_PACKAGE_SYSTEMD),y)
 PIPEWIRE_CONF_OPTS += \
-	-Dsystemd=enabled \
+	-Dlibsystemd=enabled \
 	-Dsystemd-system-service=enabled \
 	-Dsystemd-user-service=enabled
 PIPEWIRE_DEPENDENCIES += systemd
 else
 PIPEWIRE_CONF_OPTS += \
-	-Dsystemd=disabled \
+	-Dlibsystemd=disabled \
 	-Dsystemd-system-service=disabled \
 	-Dsystemd-user-service=disabled
 endif
@@ -100,7 +100,8 @@ else
 PIPEWIRE_CONF_OPTS += -Davahi=disabled
 endif
 
-ifeq ($(BR2_PACKAGE_JACK2),y)
+# uClibc does not implement thread_local
+ifeq ($(BR2_PACKAGE_JACK2):$(BR2_TOOLCHAIN_USES_UCLIBC),y:)
 PIPEWIRE_CONF_OPTS += -Dpipewire-jack=enabled -Djack=enabled
 PIPEWIRE_DEPENDENCIES += jack2
 else